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Alcohol Use Disorder: Symptomatology, Prevention and Control

Background

Alcohol use disorder (AUD), sometimes called alcoholism, is a chronic condition caused by impaired ability to stop or control alcohol intake even when it begins to affect an individual’s health and well-being. AUD can be mild, moderate, or severe, where individuals experience withdrawal when not using. Alcohol is the most commonly used psychoactive substances in Nigeria. Though some religions frowned at alcohol use, its cultural acceptance has made it a common condition in Nigeria, with a prevalence rate of 6.4% among adults. A study on problematic alcohol use in a Nigerian undergraduate population in 2022 found a prevalence of 10.4% and this was mostly among males. Excessive use of alcohol poses a great threat to individual and community health, from suicide, to depression, homicide, traffic accidents, domestic violence, and unsafe sexual behavior. This is why a proper treatment plan is crucial to help people with AUD achieve recovery and protect society at large. 

Discussion

Symptoms

Noticeable changes in mood and behavior characterize alcohol use disorder symptoms. 

  • Behavioral symptoms of AUD: increased alcohol consumption, unsuccessful attempts to limit the amount of alcohol use, continued usage despite evidence of adverse effects, and failure to meet daily responsibilities. 
  • Physical Symptoms: developing a tolerance to alcohol, experiencing withdrawal symptoms such as tremors, blackouts, sweating, and nausea when not used, also common are liver disease and gastrointestinal problems. 
  • Psychological Symptoms include: having a strong craving for alcohol, and mood disturbances like aggression, euphoria, loneliness, self-destructive behaviour, and anxiety. As much as half of the problematic users get depressed, with some becoming suicidal.

 

Clinical Findings

During psychiatric examination, signs of intoxication, cognitive impairments, mood swings, and withdrawal may be observed. Physical examination can present signs of chronic alcohol use, such as increased/decreased liver size, jaundice, ascites, and peripheral neuropathy. The examination is crucial as many clients may not report some features until when examined.

 

Differential Diagnosis

Several conditions that may present with unhealthy alcohol use include; 

  • Posttraumatic stress disorder
  • Bipolar disorder 
  • Generalized anxiety disorder and panic disorder
  • Dysthymic disorder
  • Medical conditions like Hepatic encephalopathy and delirium
  • Other Substance Use Disorders (Cannabis, opioids, and Polysubstance use).

 

Investigations

Investigations to consider during the diagnosis of AUD include:

  • Evaluation of the patient's history 
  • Use of screening questionnaires, e.g, Alcohol Use Disorders Identification Test (AUDIT), to assess the level of alcohol use, tolerance, and potential issues. 
  • The severity of AUD can be determined using DSM-5 diagnostic criteria. 
  • Drug Test: Alcohol is only seen in routine urine drug testing within 3 hours of last use, thus it may be negative on urine testing. This discordance between clinical self-report, psychometric tool assessment, and laboratory analysis underscores the need for further scrutiny and caution while using any approach as a stand-alone, especially when planning for interventions.
  • Blood alcohol levels to confirm recent use.
  • Some laboratory tests, such as liver function tests, are used to identify alcohol related organ damage. 

 

Treatment

Treatment involves the use of medications like disulfiram, naltrexone, or acamprosate to support abstinence and reduce cravings, a detoxification programme to manage acute symptoms, as well as engaging in cognitive behavioral therapy and support groups to manage the psychological aspect of the disorder. 

 

Follow-Up

Initially, patients may require evaluation within 1-2 weeks of starting treatment. Subsequent visits may increase or decrease in frequency as necessary based on adherence to treatment and changes in symptom severity.

 

Prevention and Control

Preventive measures of AUD include the following:

  • Enlightening people about the adverse health effects of alcohol use 
  • Regulation of sales and use of alcohol. 
  • Primary care settings to offer AUD routine screening programs.
  • Alcohol Abuse Treatment, Education and Rehabilitation
  • Harm reduction
  • Formation of support groups such as Alcohol Anonymous (AA)
  • Encouraging alternative leisure activities and promoting healthy lifestyles. ​

 

Conclusion and Recommendations.

Alcohol use disorder is a medical condition caused by the unhealthy use of alcohol. It's a common disorder in Nigeria due to some socioeconomic factors like poverty, unemployment, and peer pressure. The increasing prevalence of depression and problematic drinking among university students is worrisome as this will not only adversely impact their academic performance but future productivity and the risk of other psychosocial and health problems. This is due to the heavy drinking impairing judgment, memory unhealthy behaviors which could affect both immediate academic and future performance. If neglected, AUD can affect normal daily life and cause chronic health issues such as liver disease and gastrointestinal problems. Effective actions to mitigate the effects of AUD include early diagnosis, therapy, and the right medications. Finally, there is a need for prompt interventions at family, community and government levels to curb this rising menace among university students in order to secure their futures.

Interesting patient case

A 37-year-old man who has been attempting to stop taking alcohol after about 8 years of alcohol consumption showed signs of alcohol withdrawal, including tremors and agitation, during examination in the clinic. After further investigations, he was diagnosed with severe Alcohol Use Disorder and was started on a regimen of disulfiram and referred for therapy. He was monitored regularly to check his treatment progress while he continued to participate in his support group. In the course of six months, he was able to control his alcohol intake and attain total abstinence, which helped him rebuild his lost relationships and secure a new job. 

Further readings
  1. Adewuya, A. O., & Ola, B. A. (2005). Prevalence of alcohol use disorders among Nigerian university students: A comparative study. Journal of Substance Use, 10(5), 309-315.
  2. Alatishe, T., Oladele, O., Suleiman, B., Oyewole, A., Ojedokun, S., Oloyede, T., & Oladibu, O. (2022). Prevalence of Depression, Problematic Drinking and their Correlates among University Students in Southwest Nigeria. International Neuropsychiatric Disease Journal17(4), 25-36.
  3. Gureje, O., Degenhardt, L., Olley, B., Uwakwe, R., Udofia, O., Wakil, A., & Adeyemi, O. (2007). A descriptive epidemiology of substance use and substance use disorders in Nigeria during the early 21st century. Drug and Alcohol Dependence, 91(1), 1-9.
  4. Ogualili, P., Kareem, Y. A., Sham, J. D., Kareem, F. A., Davuruk, D. A., Lawal, Q. O., … & Wakawa, I. A. (2024). Level of concordance between urine drug test results and self-report among patients attending the substance use disorders clinic in Federal Neuropsychiatric Hospital Maiduguri. Orient Journal of Medicine36(3-4), 99-108.
  5. Oladeji, B. D., & Gureje, O. (2013). The comorbidity between alcohol use disorders and other mental health conditions in low- and middle-income countries. Current Opinion in Psychiatry, 26(1), 1-7.

Author's details

Reviewer's details

Alcohol Use Disorder: Symptomatology, Prevention and Control

Alcohol use disorder (AUD), sometimes called alcoholism, is a chronic condition caused by impaired ability to stop or control alcohol intake even when it begins to affect an individual’s health and well-being. AUD can be mild, moderate, or severe, where individuals experience withdrawal when not using. Alcohol is the most commonly used psychoactive substances in Nigeria. Though some religions frowned at alcohol use, its cultural acceptance has made it a common condition in Nigeria, with a prevalence rate of 6.4% among adults. A study on problematic alcohol use in a Nigerian undergraduate population in 2022 found a prevalence of 10.4% and this was mostly among males. Excessive use of alcohol poses a great threat to individual and community health, from suicide, to depression, homicide, traffic accidents, domestic violence, and unsafe sexual behavior. This is why a proper treatment plan is crucial to help people with AUD achieve recovery and protect society at large. 

  1. Adewuya, A. O., & Ola, B. A. (2005). Prevalence of alcohol use disorders among Nigerian university students: A comparative study. Journal of Substance Use, 10(5), 309-315.
  2. Alatishe, T., Oladele, O., Suleiman, B., Oyewole, A., Ojedokun, S., Oloyede, T., & Oladibu, O. (2022). Prevalence of Depression, Problematic Drinking and their Correlates among University Students in Southwest Nigeria. International Neuropsychiatric Disease Journal17(4), 25-36.
  3. Gureje, O., Degenhardt, L., Olley, B., Uwakwe, R., Udofia, O., Wakil, A., & Adeyemi, O. (2007). A descriptive epidemiology of substance use and substance use disorders in Nigeria during the early 21st century. Drug and Alcohol Dependence, 91(1), 1-9.
  4. Ogualili, P., Kareem, Y. A., Sham, J. D., Kareem, F. A., Davuruk, D. A., Lawal, Q. O., … & Wakawa, I. A. (2024). Level of concordance between urine drug test results and self-report among patients attending the substance use disorders clinic in Federal Neuropsychiatric Hospital Maiduguri. Orient Journal of Medicine36(3-4), 99-108.
  5. Oladeji, B. D., & Gureje, O. (2013). The comorbidity between alcohol use disorders and other mental health conditions in low- and middle-income countries. Current Opinion in Psychiatry, 26(1), 1-7.

Content

Author's details

Reviewer's details

Alcohol Use Disorder: Symptomatology, Prevention and Control

Alcohol use disorder (AUD), sometimes called alcoholism, is a chronic condition caused by impaired ability to stop or control alcohol intake even when it begins to affect an individual’s health and well-being. AUD can be mild, moderate, or severe, where individuals experience withdrawal when not using. Alcohol is the most commonly used psychoactive substances in Nigeria. Though some religions frowned at alcohol use, its cultural acceptance has made it a common condition in Nigeria, with a prevalence rate of 6.4% among adults. A study on problematic alcohol use in a Nigerian undergraduate population in 2022 found a prevalence of 10.4% and this was mostly among males. Excessive use of alcohol poses a great threat to individual and community health, from suicide, to depression, homicide, traffic accidents, domestic violence, and unsafe sexual behavior. This is why a proper treatment plan is crucial to help people with AUD achieve recovery and protect society at large. 

  1. Adewuya, A. O., & Ola, B. A. (2005). Prevalence of alcohol use disorders among Nigerian university students: A comparative study. Journal of Substance Use, 10(5), 309-315.
  2. Alatishe, T., Oladele, O., Suleiman, B., Oyewole, A., Ojedokun, S., Oloyede, T., & Oladibu, O. (2022). Prevalence of Depression, Problematic Drinking and their Correlates among University Students in Southwest Nigeria. International Neuropsychiatric Disease Journal17(4), 25-36.
  3. Gureje, O., Degenhardt, L., Olley, B., Uwakwe, R., Udofia, O., Wakil, A., & Adeyemi, O. (2007). A descriptive epidemiology of substance use and substance use disorders in Nigeria during the early 21st century. Drug and Alcohol Dependence, 91(1), 1-9.
  4. Ogualili, P., Kareem, Y. A., Sham, J. D., Kareem, F. A., Davuruk, D. A., Lawal, Q. O., … & Wakawa, I. A. (2024). Level of concordance between urine drug test results and self-report among patients attending the substance use disorders clinic in Federal Neuropsychiatric Hospital Maiduguri. Orient Journal of Medicine36(3-4), 99-108.
  5. Oladeji, B. D., & Gureje, O. (2013). The comorbidity between alcohol use disorders and other mental health conditions in low- and middle-income countries. Current Opinion in Psychiatry, 26(1), 1-7.
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