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Patient case: Sub-Acute Thyroiditis

Discussion

A 32-year-old woman presents with a 2-week history of a painful, swollen neck, accompanied by a sore throat, fever, and fatigue. She reports difficulty swallowing due to the discomfort and mentions that the pain occasionally radiates to her jaw and ears. She denies any recent upper respiratory infections. On examination, her thyroid gland is tender and mildly enlarged. Her vital signs reveal a low-grade fever and an elevated heart rate.

Initial lab tests show elevated thyroid hormone levels (T3, T4), and suppressed TSH levels. ESR (erythrocyte sedimentation rate) is significantly elevated, indicating inflammation. The patient is diagnosed with sub-acute (de Quervain’s) thyroiditis, a self-limiting inflammatory thyroid condition. She is started on NSAIDs for pain and inflammation management, with a plan for follow-up in a few weeks to monitor her recovery.

Questions
1. What is the primary symptom of sub-acute thyroiditis in the patient described?

a) Weight gain

b) Painful, swollen neck

c) Hair loss

d) Heat intolerance

2. Which of the following lab findings is typically elevated in sub-acute thyroiditis?

a) Blood glucose

b) ESR (Erythrocyte Sedimentation Rate)

c) Calcium levels

d) Potassium levels

3. What treatment is most appropriate for the pain and inflammation associated with sub-acute thyroiditis?

a) Antibiotics

b) Corticosteroids

c) NSAIDs (Non-Steroidal Anti-Inflammatory Drugs)

d) Antithyroid medication

4. Which of the following complications is commonly associated with sub-acute thyroiditis?

a) Hypothyroidism

b) Hyperparathyroidism

c) Diabetes

d) Anemia

Reveal answers

Answers

1. b) Painful, swollen neck

2. b) ESR (Erythrocyte Sedimentation Rate)

3. c) NSAIDs (Non-Steroidal Anti-Inflammatory Drugs)

4. a) Hypothyroidism

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