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Polypharmacy in an Elderly Individual

Discussion

Mrs. K is an 82-year-old woman living in a rural village with her family. She presents to the local clinic with complaints of dizziness, frequent falls, and fatigue. Over the years, she has been diagnosed with hypertension, type 2 diabetes, osteoarthritis, and chronic heart failure.

Her medication regimen includes:

Amlodipine 5 mg for hypertension

Metformin 500 mg twice daily for diabetes

Furosemide 40 mg for heart failure

Paracetamol 500 mg as needed for osteoarthritis pain

Glyburide 2.5 mg for blood sugar control

Recently, her family added a traditional herbal remedy for joint pain, which she has been taking daily. Mrs. K reports that her symptoms have worsened over the past few weeks, and she has experienced increased confusion and difficulty maintaining her balance.

Upon review, it is found that Mrs. K is suffering from polypharmacy, where drug interactions, particularly between her antihypertensive, diuretic, and hypoglycaemic medications, have contributed to her symptoms of dizziness and falls. Furthermore, the addition of the herbal remedy may be complicating her health further by interacting with her prescribed medications. The clinician recognizes the need to reassess her medication regimen to minimize adverse effects while maintaining control of her chronic conditions.

Questions
1. What is the most likely cause of Mrs. K's dizziness and frequent falls?

A). Anaemia

B). Dehydration

C). Polypharmacy and drug interactions

D). Stroke

 

 

 

2. Which of the following medications could be contributing to Mrs. K’s increased risk of falls?

A). Paracetamol

B). Amlodipine

C). Metformin

D). Herbal remedy

3. In elderly patients like Mrs. K, which of the following factors increases the risk of adverse drug reactions?

A). Use of over-the-counter medications only

B). Polypharmacy and age-related changes in drug metabolism

C). Living in a rural area

D). Use of only traditional medicine

4. What is the most appropriate first step in managing Mrs. K’s condition?

A). Increase the dose of her diuretic

B). Stop all medications

C). Reassess her medications to reduce unnecessary prescriptions and monitor for drug interactions

D). Prescribe additional medications to control her symptoms

Reveal answers

Answers

  1. C). Polypharmacy and drug interactions
  2. B). Amlodipine
  3. B). Polypharmacy and age-related changes in drug metabolism
  4. C). Reassess her medications to reduce unnecessary prescriptions and monitor for drug interactions