Skip to content

Patient Case: Recurrent Itchy Rash in a Young Adult

Discussion

A 22-year-old university student presents with a history of recurrent, intensely itchy rashes that have affected her elbows, knees, and neck since childhood. The rash worsens during cold, dry seasons and after prolonged exposure to fragranced soaps or wool clothing. She has a history of asthma and allergic rhinitis.

Over the past month, her symptoms have flared up, with red, dry, and scaly patches appearing on her hands and face. She reports frequent scratching, which sometimes leads to oozing and crusting. Over-the-counter creams provide minimal relief.

On examination, there are erythematous, lichenified plaques on the flexural surfaces of the elbows and knees, as well as dry, excoriated patches on her hands. There are no signs of bacterial infection. A clinical diagnosis of atopic dermatitis is made.

She is advised to avoid known triggers, use fragrance-free emollients regularly, and apply topical corticosteroids during flare-ups. An antihistamine is prescribed for itch relief, and she is educated on maintaining proper skin hydration.

Questions
1. What is the most likely diagnosis in this patient?

a) Contact dermatitis
b) Psoriasis
c) Atopic dermatitis
d) Seborrheic dermatitis

2. Which of the following is a key feature that supports the diagnosis of atopic dermatitis?

a) Lesions with silvery scales on extensor surfaces
b) Chronic, itchy rash in flexural areas with a history of asthma
c) Yellow, greasy scales on the scalp and eyebrows
d) Vesicular rash following exposure to an irritant

3. Which of the following is the best initial treatment for this patient?

a) Systemic corticosteroids
b) Antifungal creams
c) Regular emollient use and topical corticosteroids for flare-ups
d) Oral antibiotics

4. Which of the following lifestyle modifications can help prevent flare-ups?

a) Avoiding frequent use of moisturizers to let the skin "breathe"
b) Wearing wool clothing to keep warm in cold weather
c) Using fragrance-free emollients and avoiding harsh soaps
d) Taking long, hot showers to soothe itching

Reveal answers

Answers

  1. (c) Atopic dermatitis
    • The patient’s history of chronic, itchy rashes in flexural areas, along with asthma and allergic rhinitis, strongly suggests atopic dermatitis (AD). Psoriasis (b) typically presents with silvery scales on extensor surfaces, seborrheic dermatitis (d) occurs in oily areas, and contact dermatitis (a) usually follows direct exposure to an irritant or allergen.
  2. (b) Chronic, itchy rash in flexural areas with a history of asthma
    • Atopic dermatitis is a chronic inflammatory skin condition often associated with personal or family history of atopy (asthma, allergic rhinitis, eczema). Silvery scales on extensor surfaces (a) suggest psoriasis, yellow greasy scales (c) indicate seborrheic dermatitis, and vesicular rash after irritant exposure (d) is characteristic of contact dermatitis.
  3. (c) Regular emollient use and topical corticosteroids for flare-ups
    • The cornerstone of atopic dermatitis management includes frequent use of fragrance-free emollients to maintain skin hydration and topical corticosteroids to reduce inflammation during flare-ups. Systemic corticosteroids (a) are not first-line due to side effects, antifungal creams (b) are ineffective for AD, and oral antibiotics (d) are only needed if there is secondary infection.
  4. (c) Using fragrance-free emollients and avoiding harsh soaps
    • Regular moisturizing with fragrance-free emollients and avoiding harsh soaps help restore the skin barrier and prevent flare-ups. Wool clothing (b) can irritate the skin, and long, hot showers (d) worsen dryness. Avoiding moisturizers (a) is incorrect, as hydration is crucial in managing atopic dermatitis.

Are you a Medical Doctor?