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Patient case: Male Infertility.

Patient details
Patient details.
Mr. KM Age: 32 years Location: Accra, Ghana Chief Complaint: Mr. KM and his wife, A, have been trying to conceive for the past three years without success. They present to the clinic seeking help for their infertility.
Patient case fields
Medical History

Mr. KM has no significant past medical history. He has never had any major illnesses, surgeries, or hospitalisations. There is no family history of infertility. He works as a civil engineer and has a relatively sedentary lifestyle. He does not smoke, drinks alcohol occasionally, and reports no recreational drug use. Mrs. KM has regular menstrual cycles, and a gynaecological evaluation has ruled out any apparent issues on her side.

Social History

Mr. KM and his wife live in a suburban area of Accra. They have access to a balanced diet but report occasional exposure to environmental pollutants from nearby industrial activities. The couple is under some stress due to societal pressure to conceive.

Examination Findings

Physical examination of Mr. KM is unremarkable. His vital signs are within normal limits, and there are no signs of hormonal imbalances or physical abnormalities in the reproductive organs.

Investigations

A semen analysis was conducted, revealing a significantly low sperm count (oligospermia) with poor motility and morphology. Hormonal profile tests show normal levels of testosterone, follicle-stimulating hormone (FSH), and luteinising hormone (LH). No varicocele or other physical abnormalities were detected on scrotal ultrasound.

Diagnosis

Male infertility secondary to low sperm count, possibly exacerbated by environmental factors and lifestyle.

Management
  1. Lifestyle Modifications:

   - Encourage regular exercise and a balanced diet rich in antioxidants to improve sperm quality.

   - Advise reducing alcohol intake and avoiding exposure to environmental toxins where possible.

   - Stress management techniques, including counselling and relaxation exercises.

  1. Medical Treatment:

   - Consider the use of supplements such as folic acid, zinc, and coenzyme Q10, which may help improve sperm count and motility.

   - If no improvement is seen in six months, consider assisted reproductive techniques, such as intrauterine insemination (IUI) or in vitro fertilisation (IVF).

  1. Follow-Up:

   - Repeat semen analysis in three to six months to assess the response to lifestyle changes and medical treatment.

   - Regular counselling sessions to support the couple emotionally throughout the treatment process.

Discussion
Discussion

With appropriate management and potential use of assisted reproductive technologies, there is a fair chance of achieving conception. However, continuous monitoring and adjustment of treatment may be required.

Questions
1. What is the primary factor contributing to Mr. KM 's infertility?

   (A). Hormonal imbalance  

   (B). Low sperm count (oligospermia)  

   (C). Varicocele  

   (D). Irregular menstrual cycles of his wife  

2. Which of the following lifestyle changes was recommended to Mr. KM to improve his sperm count?  

   (A). Increased alcohol consumption  

   (B). Reduced physical activity  

   (C). Stress management techniques  

   (D). Exposure to industrial pollutants  

3. What was the result of Mr. KM 's hormonal profile tests? 

   (A). Elevated testosterone levels  

   (B). Normal hormone levels (testosterone, FSH, LH)  

   (C). Low follicle-stimulating hormone (FSH)  

   (D). High luteinising hormone (LH)  

4. If lifestyle modifications and medical treatments do not improve Mr. KM 's condition, what is the next recommended step? 

   (A). Surgical intervention  

   (B). Use of assisted reproductive techniques like IUI or IVF  

   (C). Long-term use of testosterone replacement therapy  

   (D). No further treatment  

Reveal answers

Answers

  1. (B). Low sperm count (oligospermia)
  2. (C). Stress management techniques
  3. (B). Normal hormone levels (testosterone, FSH, LH)
  4. (B). Use of assisted reproductive techniques like IUI or IVF

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