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Patient case: Constrictive Pericarditis

Discussion

A 55-year-old male from a rural village in sub-Saharan Africa presents to the clinic with progressive shortness of breath, fatigue, and swelling in his legs over the past 6 months. He reports that the symptoms started gradually and have worsened, particularly after exertion. He also mentions experiencing intermittent chest discomfort but denies any sharp or pleuritic pain. He has a history of multiple episodes of untreated acute pericarditis in the past, with no significant medical follow-up. The patient has had no known trauma or infections recently.

On physical examination, the patient appears dyspnoeic at rest with signs of right-sided heart failure, including bilateral lower extremity oedema, jugular venous distension, and hepatomegaly. His blood pressure is 110/70 mmHg, heart rate is 85 beats per minute, and respiratory rate is slightly elevated. A prominent pericardial knock is heard on auscultation. An ECG shows low voltage QRS complexes, and a chest X-ray reveals calcification of the pericardium. Echocardiography confirms the diagnosis of constrictive pericarditis, with thickened, non-compliant pericardium limiting diastolic filling of the heart.

The patient is referred for further evaluation, including potential surgical intervention, and is started on diuretics to manage the symptoms of heart failure. He is also advised to avoid strenuous activity and to follow up regularly with a cardiologist.

Questions
1. What is the most likely diagnosis for this patient based on his symptoms and diagnostic findings?

A) Acute pericarditis

B) Constrictive pericarditis

C) Pulmonary hypertension

D) Chronic obstructive pulmonary disease (COPD)

2. Which of the following physical exam findings is most suggestive of constrictive pericarditis in this patient?

A) Pericardial friction rub

B) Prominent pericardial knock

C) S3 gallop

D) Pitting oedema in both upper limbs

3. What is the most characteristic finding on chest X-ray in a patient with constrictive pericarditis?

A) Enlarged heart with cardiomegaly

B) Pericardial calcification

C) Pleural effusion

D) Pulmonary congestion

4. What is the most appropriate initial management for this patient with constrictive pericarditis?

A) Antibiotics for bacterial infection

B) Diuretics for heart failure symptoms

C) Steroids to reduce inflammation

D) Immediate surgical intervention

Reveal answers

Answers

  1. B) Constrictive pericarditis
  2. B) Prominent pericardial knock
  3. B) Pericardial calcification
  4. B) Diuretics for heart failure symptoms

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