Author's details
- Dr. Khashau Eleburuike
- MBBS (Ilorin) MSc. Global Health Karolinska Institute.
- Resident doctor in family medicine in Northern Sweden.
Reviewer's details
- Dr. Gboyega Olarinoye
- MBBS, FMCP.
- Dermatologist FMC Keffi Nassarawa State. Nigeria
Pemphigus vulgaris
Background
Pemphigus vulgaris in darker-skinned individuals can present as painful, fragile blisters and erosions that may leave behind areas of hyperpigmentation once healed. The condition affects both the skin and mucous membranes, making it difficult to manage due to potential scarring and pigment changes. They are autoimmune conditions. Treatment typically includes topical and systemic corticosteroids, immunosuppressive agents like rituximab, and careful wound care to prevent infection and minimize pigmentation alterations.
Lesion image
Pemphigus foliaceus . Erythemato us-ulceroussquamouscrusty plaques (like mud splashes) disseminated on patient's back
https://www.scielo.br/j/abd/a/M6GwT4pRNH7xDySBrKFCPPC/?lang=en
References
- Carla Andréa Avelar Pires Viviane Brito Viana Fernando Costa Araújo Silvia Ferreira Rodrigues Müller Miguel Saraty de Oliveira Francisca Regina Oliveira Carneiro. Evaluation of cases of pemphigus vulgaris and pemphigus foliaceus from a reference service in Pará state, Brazil*. 2014 Jul-Aug;89(4).
- Di Lernia V, Casanova DM, Goldust M, Ricci C. Pemphigus vulgaris and bullous pemphigoid: update on diagnosis and treatment. Dermatology practical & conceptual. 2020 Jul;10(3).
- Kayani M, Aslam AM. Bullous pemphigoid and pemphigus vulgaris. bmj. 2017 Jun 8;357.