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Pemphigus foliaceus

Background

Pemphigus foliaceus, common in sub-Saharan Africa, is an autoimmune blistering disorder affecting the skin, often triggered by environmental factors like UV exposure or infections. It presents with superficial, scaly lesions primarily on the face, scalp, and trunk. Treatment includes systemic corticosteroids, azathioprine, or mycophenolate, along with wound care and infection prevention in resource-limited settings.

Lesion image

Pemphigus foliaceus . Erythemato us-ulceroussquamouscrusty plaques (like mud splashes) disseminated on patient's back

https://www.scielo.br/j/abd/a/M6GwT4pRNH7xDySBrKFCPPC/?lang=en  

References
  • Carla Andréa Avelar Pires Viviane Brito Viana Fernando Costa Araújo Silvia Ferreira Rodrigues Müller Miguel Saraty de Oliveira Francisca Regina Oliveira Carneiro. Evaluation of cases of pemphigus vulgaris and pemphigus foliaceus from a reference service in Pará state, Brazil*. 2014 Jul-Aug;89(4).
  • James KA, Culton DA, Diaz LA. Diagnosis and clinical features of pemphigus foliaceus. Dermatologic clinics. 2011 Jul 1;29(3):405-12.
  • Melchionda V, Harman KE. Pemphigus vulgaris and pemphigus foliaceus: an overview of the clinical presentation, investigations and management. Clinical and experimental dermatology. 2019 Oct 1;44(7):740-6.