Cornification Disorder refers to a group of skin conditions where the natural process of skin cell formation and shedding becomes abnormal, leading to thickened, scaly, or rough patches on the skin. In Sub-Saharan Africa, where climate, nutrition, and genetics play key roles, early diagnosis and proper dermatological care are vital to prevent complications and discomfort. Understanding cornification disorders helps promote skin health awareness and encourages individuals to seek timely medical attention for healthier, clearer skin.