Author's details
- Dr. Khashau Eleburuike
- MBBS (Ilorin) MSc. Global Health Karolinska Institute.
- Resident doctor in family medicine in Northern Sweden.
Reviewer's details
- Dr. Gboyega Olarinoye
- MBBS, FMCP.
- Dermatologist FMC Keffi Nassarawa State. Nigeria
Epidermolysis Bullosa Acquisita
Background
Epidermolysis bullosa acquisita in darker-skinned individuals typically presents as fragile skin with blisters and erosions that heal with dark pigmentation or scarring. The condition can lead to extensive areas of post-inflammatory hyperpigmentation, especially in trauma-prone regions like the hands, feet, and elbows. Treatment includes corticosteroids, immunosuppressive agents, and careful wound care to prevent infection and reduce blister formation, while addressing any pigmentation changes with supportive skin care therapies.
Lesion image
Tense blisters, crusts, and milia (indicated by arrows) on the (a) dorsum of hands and (b) on lower legs
https://www.e-ijd.org/articles/2016/61/3/images/IndianJDermatol_2016_61_3_329_182420_f1.jpg
References
- Goyal N, Rao R, Balachandran C, Pai S, Bhogal BS, Schmidt E, et al. Childhood Epidermolysis Bullosa Acquisita: Confirmation of Diagnosis by Skin Deficient in Type VII Collagen, Enzyme-linked Immunosorbent Assay, and Immunoblotting. 2016 May-Jun;61(3):329-332.
- Gupta R, Woodley DT, Chen M. Epidermolysis bullosa acquisita. Clinics in dermatology. 2012 Jan 1;30(1):60-9.
- Koga H, Prost-Squarcioni C, Iwata H, Jonkman MF, Ludwig RJ, Bieber K. Epidermolysis bullosa acquisita: the 2019 update. Frontiers in medicine. 2019 Jan 10;5:362.
- Kim JH, Kim SC. Epidermolysis bullosa acquisita. Journal of the European Academy of Dermatology and Venereology. 2013 Oct;27(10):1204-13.