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Bullous Pemphigoid

Background

Bullous pemphigoid in darker-skinned individuals presents as large, tense blisters on normal or darkened skin, which may heal with post-inflammatory hyperpigmentation. The condition can cause significant discomfort and scarring, especially if blisters rupture and become infected. Treatment typically involves systemic corticosteroids, immunosuppressive medications like azathioprine, and topical corticosteroids to reduce inflammation and control blister formation while minimizing pigmentation changes.

Lesion image

Lichenoid erythrodermic bullous pemphigoid of the African patient  Lichenoid erythrodermic bullous pemphigoid of the African patient - ScienceDirect  

References
  • Joly, MD, PhDa S. Tanasescu, MDa P. Wolkenstein, MD, PhDb J. Revuz, MDb F. Tron, MD, PhDa Ph. Lauret, MDa Show all authors. Lichenoid erythrodermic bullous pemphigoid of the African patient
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  • Cholera M, Chainani-Wu N. Management of pemphigus vulgaris. Advances in therapy. 2016 Jun;33:910-58.
  • Venugopal SS, Murrell DF. Diagnosis and clinical features of pemphigus vulgaris. Dermatologic clinics. 2011 Jul 1;29(3):373-80.