Stevens-Johnson syndrome (SJS) in darker-skinned individuals presents with widespread painful, dusky or purplish lesions, and severe mucous membrane involvement, which may be less noticeable initially compared to lighter skin tones. The condition can result in significant hyperpigmentation or scarring after healing. Treatment requires immediate discontinuation of the causative drug, hospitalization for supportive care, pain management, and in severe cases, systemic corticosteroids or immunoglobulin therapy to reduce inflammation and prevent complications.