Amoeba cutis, a rare skin infection caused by the *Naegleria fowleri* amoeba, typically presents in darker-skinned individuals as painful, red, or dark lesions that may resemble other skin conditions. This infection, which is usually acquired from exposure to contaminated freshwater, can lead to skin necrosis and systemic involvement, especially if not diagnosed and treated promptly. Treatment requires aggressive antifungal therapy, such as amphotericin B, alongside supportive care, and early intervention is critical for improving outcomes in severe cases.