Human papillomavirus (HPV) in darker-skinned individuals can cause warts that appear as raised, flesh-coloured or darker lesions, which may be more difficult to detect depending on the type and location. HPV infections can lead to an increased risk of certain cancers, particularly in the cervix, anus, and oropharynx, with darker skin potentially masking early signs of infection. Treatment options include topical therapies like imiquimod, cryotherapy, and laser treatment to remove warts, while the HPV vaccine can help prevent certain strains associated with cancer risk.