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Multiple Sclerosis

Discussion

A 34-year-old woman presented to the neurology clinic with a history of recurrent neurological symptoms that had developed over the past year. She reported experiencing episodes of numbness and tingling in her right arm and leg, which lasted for several days and then resolved. In addition, she noted episodes of blurred vision in her left eye that would come and go, often accompanied by a dull headache.

During her examination, the physician conducted a thorough neurological assessment. The patient exhibited diminished sensation in her right arm and leg, along with a slight weakness in her right hand. The eye examination revealed a relative afferent pupillary defect in the left eye, and the physician noted that she appeared to have a positive Romberg sign.

Given her symptoms, the physician recommended magnetic resonance imaging (MRI) of the brain and spinal cord to evaluate for lesions characteristic of multiple sclerosis (MS). The MRI results showed multiple hyperintense lesions in the periventricular and subcortical white matter, consistent with demyelination.

The diagnosis of relapsing-remitting multiple sclerosis was confirmed, and the physician discussed treatment options with the patient. She was started on a disease-modifying therapy (DMT) to help reduce the frequency of relapses and slow the progression of the disease. The patient was also referred to a physical therapist for rehabilitation exercises to improve strength and coordination.

Throughout her follow-up appointments, the patient was educated about MS and the importance of adhering to her treatment plan. Lifestyle modifications, including stress management techniques and regular exercise, were also discussed to help manage her symptoms and enhance her quality of life.

Questions
1. What primary symptoms did the patient report that led her to seek medical attention?

a) Persistent headaches and nausea

b) Recurrent episodes of numbness and tingling in her right arm and leg, and blurred vision

c) Severe fatigue and weight loss

d) Dizziness and loss of balance

2. What did the neurological examination reveal about the patient?

a) Normal sensation and strength in all limbs

b) Diminished sensation in her right arm and leg, with slight weakness in her right hand

c) Increased muscle tone and spasticity in the lower extremities

d) Complete paralysis on one side of the body

3. What diagnostic imaging was used to evaluate the patient's condition?

a) Computed Tomography (CT) scan

b) Electromyography (EMG)

c) Magnetic Resonance Imaging (MRI)

d) Ultrasound of the brain

4. What was the prescribed treatment plan for the patient diagnosed with relapsing-remitting multiple sclerosis?

a) High-dose corticosteroids for symptom relief

b) Disease-modifying therapy (DMT) to reduce relapse frequency

c) Antidepressants to manage fatigue

d) Pain management with opioids

Reveal answers

Answers

1. b) Recurrent episodes of numbness and tingling in her right arm and leg, and blurred vision

2. b) Diminished sensation in her right arm and leg, with slight weakness in her right hand

3. c) Magnetic Resonance Imaging (MRI)

4. b) Disease-modifying therapy (DMT) to reduce relapse frequency