Gastric Cancer
A 68-year-old female presents to the clinic with persistent abdominal discomfort, unexplained weight loss of 10 kg over the past three months, and early satiety. She also reports occasional nausea and vomiting after meals. Her medical history is significant for mild hypertension, and she has no prior surgeries.
On physical examination, the patient appears thin and pale. There is mild epigastric tenderness, but no palpable masses are noted. Laboratory tests reveal anemia with a hemoglobin level of 10 g/dL and elevated levels of tumor markers, specifically CA 19-9. An upper gastrointestinal endoscopy is performed, which reveals an irregular mass in the gastric body, and biopsy results confirm poorly differentiated adenocarcinoma.
The patient is staged as having locally advanced gastric cancer and is referred to an oncology team for management. A treatment plan including neoadjuvant chemotherapy is discussed, followed by surgical resection. She begins chemotherapy with close monitoring for side effects and is scheduled for a follow-up in four weeks to assess her response to treatment.
a). Severe chest pain and shortness of breath
b). Abdominal discomfort, weight loss, and early satiety
c). Fever and chills
d). Jaundice and pruritus
a). Abdominal ultrasound
b). CT scan of the abdomen
c). Upper gastrointestinal endoscopy
d). MRI of the abdomen
a). Squamous cell carcinoma
b). Gastroesophageal junction adenocarcinoma
c). Poorly differentiated adenocarcinoma of the stomach
d). Lymphoma
a). Immediate surgical resection
b). Neoadjuvant chemotherapy followed by surgical resection
c). Palliative care only
d). Radiation therapy
Answers
- b). Abdominal discomfort, weight loss, and early satiety
- c). Upper gastrointestinal endoscopy
- c). Poorly differentiated adenocarcinoma of the stomach
- b). Neoadjuvant chemotherapy followed by surgical resection.