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Prescription Cascade in the Elderly

Discussion

Mrs. L is a 79-year-old woman who visits her doctor due to persistent swelling in her ankles and joint pain. She has a history of hypertension and osteoporosis, for which she has been taking amlodipine for blood pressure control and alendronate for bone health.

A few months ago, she was prescribed ibuprofen for her joint pain. Soon after, she began experiencing stomach discomfort and heartburn, for which her doctor prescribed omeprazole, a proton pump inhibitor (PPI). After starting the omeprazole, Mrs. L developed persistent swelling in her ankles, leading her physician to prescribe furosemide, a diuretic, to reduce the fluid retention.

At her current visit, Mrs. L complains of increased fatigue and dizziness. Upon reviewing her medication history, it is evident that a prescription cascade occurred. The ibuprofen caused gastrointestinal issues, leading to the omeprazole prescription. The omeprazole may have worsened her amlodipine-induced swelling, prompting the furosemide, which is now contributing to her dizziness and fatigue.

Her doctor recognizes the need to simplify her medication regimen, discontinuing unnecessary prescriptions and addressing the root cause of her symptoms to prevent further complications.

Questions
1. What initially triggered the prescription cascade in Mrs. L's case?

A). Amlodipine

B). Alendronate

C). Ibuprofen

D). Furosemide

 

 

 

 

2. What medication was prescribed to address Mrs. L’s gastrointestinal discomfort caused by ibuprofen?

A). Furosemide

B). Omeprazole

C). Alendronate

D). Amlodipine

3. What was the likely reason for Mrs. L’s ankle swelling that led to the prescription of furosemide?

A). Heart failure

B). Omeprazole causing fluid retention

C). Amlodipine-induced side effect

D). Alendronate causing swelling

4. What is the most appropriate intervention to address Mrs. L’s prescription cascade?

A). Increase the dose of furosemide

B). Discontinue ibuprofen and review her medication regimen

C). Add another medication to treat her dizziness

D). Prescribe a stronger diuretic

Reveal answers

Answers

  1. C). Ibuprofen
  2. B). Omeprazole
  3. C). Amlodipine-induced side effect
  4. B). Discontinue ibuprofen and review her medication regimen