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Endometrial Cancer.

Patient details
Patient details.
Mrs. FD Age: 62 years Location: Bamako, Mali Presenting Complaints Mrs. FD presents with postmenopausal vaginal bleeding that has persisted for two months.
Patient case fields
Medical History

Mrs. FD went through menopause ten years ago and has not experienced any menstrual bleeding until recently. She noticed light bleeding initially, which has become heavier over time. She also reports mild lower abdominal pain and bloating. She has a history of hypertension, which is well-managed with medication. Mrs. FD has no known family history of cancer. She has never had a Pap smear or other gynaecological screening.

Social History

Mrs. FD lives in an urban area of Bamako with her husband. She is a homemaker and has four adult children. She does not smoke or drink alcohol and follows a diet that is mostly high in carbohydrates and low in fresh fruits and vegetables. She has limited access to regular healthcare services.

Examination Findings

On examination, Mrs. FD appears well but anxious. A pelvic examination reveals a slightly enlarged, non-tender uterus. There are no obvious signs of infection or other abnormalities on the external genitalia.

Investigations

A transvaginal ultrasound reveals a thickened endometrium. An endometrial biopsy is performed and confirms the diagnosis of endometrial adenocarcinoma. A pelvic MRI shows that the cancer is confined to the uterus with no evidence of spread to other organs.

Diagnosis

Early-stage endometrial adenocarcinoma.

Management Plan

1. Surgical Treatment:
- A total hysterectomy with bilateral salpingo-oophorectomy (removal of the uterus, fallopian tubes, and ovaries) is recommended as the primary treatment.
- Lymph node sampling may be performed during surgery to assess for any spread of the disease.
2. Adjuvant Therapy:
- Depending on the surgical findings, consider adjuvant radiation therapy to reduce the risk of recurrence, especially if there is evidence of lymph node involvement or other risk factors.

Outcome

- Regular follow-up visits will be scheduled to monitor for any signs of recurrence.
- Postoperative care will include pain management, counselling, and support to help Mrs. Diallo adjust to life after surgery.

Discussion
Discussion

Given the early-stage diagnosis and the plan for surgical treatment, Mrs. FD 's prognosis is generally favourable. With appropriate treatment and follow-up, there is a high likelihood of successful management and long-term survival.

Questions
1. What was the primary symptom that led Mrs. FD to seek medical attention?  

   (A). Severe back pain  

   (B). Postmenopausal vaginal bleeding  

   (C). Chronic cough  

   (D). Unexplained weight gain  

2. What did the transvaginal ultrasound reveal in Mrs. FD’s case? 

   (A). Normal endometrial thickness  

   (B). A thickened endometrium  

   (C). Ovarian cysts  

   (D). A fibroid in the uterus  

3. What was the confirmed diagnosis after the endometrial biopsy? 

   (A). Endometrial hyperplasia  

   (B). Cervical cancer  

   (C). Endometrial adenocarcinoma  

   (D). Ovarian cancer  

4. What is the recommended initial treatment for Mrs. FD 's early-stage endometrial adenocarcinoma?

   (A). Hormone therapy  

   (B). Total hysterectomy with bilateral salpingo-oophorectomy  

   (C). Chemotherapy  

   (D). Watchful waiting  

Reveal answers

Answers

  1. (B). Postmenopausal vaginal bleeding
  2. (B). A thickened endometrium
  3. (C). Endometrial adenocarcinoma
  4. (B). Total hysterectomy with bilateral salpingo-oophorectomy